Gamma radiation exposure facilities, Stockholm University Centre for Radiation Protection Research

Gamma radiation exposure facilities, Stockholm University Centre for Radiation Protection Research

Gamma (137 Cs) exposure facilities for high or low dose rate exposures are available for the radiation of e.g cells, cell cultures, DNA and proteins.

Description

Two high dose rate gamma (137 Cs) exposure facilities are available: a Gammacell 1000, with a dose rate of 10 Gy/min, and a Scanditronix, with a dose rate of 0.6 Gy/min. The facilities are mainly used for the irradiation of microorganisms, eukaryotic cells, larger objects and samples of DNA and protein. The equipment can be used by other researchers, and we are also interested in collaborations with other research groups.

Two low dose rate gamma (137 Cs) exposure facility for chronic exposure of cells in culture is available.

The dose rate can be varied between 1-50 mGy/hour and cells be chronically exposed for days or weeks at 37 C, 5% Co2 under humidified conditions.

See our research interests on our website.

Infrastructure/Methods

The Gammacell 1000 facility is mainly used for exposure of microorganisms, eukaryotic cells and samples of DNA and protein. It has a rotating cylindrical exposure chamber with a diameter of 7.5 cm and a height of 15 cm. The dose rate can be reduced. The equipment is semi automatic, e.g. the exposure will be stopped at a preset time. The cylindrical exposure chamber is loaded with the samples (tubes, plates etc) to be exposed. Exposure temperature is around 22oC (room temperature) but ice or dry ice can be added to the exposure chamber if needed.

The Scanditronix facility is mainly used for exposure of cells in culture. It has an exposure chamber that measures 15x15 cm with a height of 10 cm. The dose rate can be reduced. The equipment is semi automatic, e.g. the exposure will be stopped at a preset time. Exposure temperature is around 22oC (room temperature) but ice or dry ice can be added to the exposure chamber if needed.

The low dose rate sources for chronic exposure of cells in culture are constructed in house and used for low dose exposures (1 mGy and higher) or chronic low dose rate exposures 1-50 mGy/hour under standard cell culture conditions.

Practical information

Access to the equipment is only possible after agreement. The staff at SU has priority. Use, experimental advice and also service is available at a self cost basis.

To use the radiation sources a “Driving license” is needed, to assure that the equipment is used only by those with adequate experience.

Please contact us for more information.

Interested in Industry collaboration
Svante Arrhenius väg 16 E+F
Stockholms University
106 91 Stockholm
+46 (0)8 16 41 09